Тhe Global Health Cluster (GHC) COVID-19 Task Team conducted two studies simultaneously – an online survey for all country health clusters and key informant interviews in six country health clusters - to identify good practices and to better understand the technical and operational challenges faced by Health Clusters and partners in the COVID-19 response and in the efforts to maintain essential health services in humanitarian settings. Shared findings include the increased operational constraints being faced, significant resource scarcity and reported technical gaps. Requests were made for additional support for shared learning and context-appropriate guidance relevant for humanitarian settings where resources are scarce.