OCHA released the 2021 Global Humanitarian Overview with 235 million people in need across 56 countries, which will require $35 billion. The overview highlights how COVID-19 has triggered the deepest global recession since the 1930s and how the pandemic has hindered essential health services in almost every country. More than five million children under five years of age face the threats of cholera and acute watery diarrhea. There is a renewed call to support local communities in meeting humanitarian needs, asking for greater support and funding to local and national NGOs. The overview highlights some good practices in inter-agency coordinated appeals but also highlights that humanitarian organizations, particularly NGOs and local responders, are suffering from severe underfunding.